Universal behavior of localization of residue fluctuations in globular proteins

Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Apr;67(4 Pt 1):041909. doi: 10.1103/PhysRevE.67.041909. Epub 2003 Apr 25.

Abstract

Localization properties of residue fluctuations in globular proteins are studied theoretically by using a Gaussian network model. Participation ratio for each residue fluctuation mode is calculated. It is found that the relationship between participation ratio and frequency is similar for all globular proteins, indicating a universal behavior in spite of their different size, shape, and architecture.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Models, Statistical
  • Myoglobin / chemistry
  • Normal Distribution
  • Protein Conformation
  • Protein Structure, Secondary
  • Proteins / chemistry*

Substances

  • Myoglobin
  • Proteins