Abstract
In Yersinia pestis, the siderophore-dependent yersiniabactin (Ybt) iron transport system and heme transport system (Hmu) have putative TonB-dependent outer membrane receptors. Here we demonstrate that hemin uptake and iron utilization from Ybt are TonB dependent. However, the Yfe iron and manganese transport system does not require TonB.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacterial Proteins / genetics
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Bacterial Proteins / physiology*
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Escherichia coli Proteins / genetics
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Heme / metabolism*
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Hemeproteins / metabolism*
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Iron / metabolism*
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Membrane Proteins / genetics
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Membrane Proteins / physiology*
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Protein Transport
Substances
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Bacterial Proteins
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Escherichia coli Proteins
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ExbB protein, E coli
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HasB protein, Serratia marcescens
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Hemeproteins
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Membrane Proteins
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tonB protein, Bacteria
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tonB protein, E coli
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exbD protein, E coli
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Heme
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Iron