Relief of symptoms in patients with group A beta-hemolytic streptococcus tonsillopharyngitis: comparison between telithromycin and penicillin V

Scand J Infect Dis. 2003;35(4):223-5. doi: 10.1080/0036554021000027021.

Abstract

This study compared the resolution of symptoms in patients with group A beta-hemolytic streptococcus tonsillopharyngitis treated with 5 d of telithromycin 800 mg once daily, or 10 d of penicillin V 500 mg 3 times daily. At days 3-5 of treatment, the mean improvement in total symptom score was greater with telithromycin than with penicillin V (p = 0.042). Thus, telithromycin provided faster symptom relief than penicillin V.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Ketolides*
  • Macrolides*
  • Male
  • Patient Satisfaction
  • Penicillin V / administration & dosage*
  • Pharyngitis / complications
  • Pharyngitis / diagnosis
  • Pharyngitis / drug therapy*
  • Probability
  • Severity of Illness Index
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / drug therapy*
  • Streptococcus pyogenes / drug effects*
  • Streptococcus pyogenes / isolation & purification
  • Tonsillitis / complications
  • Tonsillitis / diagnosis
  • Tonsillitis / drug therapy*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Ketolides
  • Macrolides
  • telithromycin
  • Penicillin V