Ossiculoplasty with total hydroxylapatite prostheses anatomical and functional outcomes

Otol Neurotol. 2003 Jul;24(4):543-7. doi: 10.1097/00129492-200307000-00003.

Abstract

Objective: To evaluate the results of partial and total ossicular reconstruction prostheses entirely made of hydroxylapatite.

Study design: A retrospective review of cases followed-up between 1997 and 2000.

Setting: Tertiary referral center.

Patients: One hundred adult patients (60 men and 40 women) were studied. The mean age was 55 years (range, 25 to 65 years). Fifty patients had a previous tympanoplasty. The series included 45 cholesteatomas (45%), 37 chronic otitis media without cholesteatoma (37%), 13 retraction pockets (13%), and 5 posttraumatic ossicular displacements (5%).

Intervention: A one-stage ossiculoplasty with a partial ossicular reconstruction prosthesis (n = 65) or a total ossicular reconstruction prosthesis (n = 35) was performed. This was associated with a simple mastoidectomy in 70 cases and a radical mastoidectomy in 10 cases.

Main outcome measures: All patients were followed-up at 1 year, and 50 were reexamined 2 years after surgery. Clinical and audiometric data were collected in a database at each visit.

Results: A prosthetic extrusion was noted in two cases (2%). A prosthetic displacement occurred in 10 cases (10%). A revision surgery was carried out in 10 cases because of an ossiculoplasty failure or a disease recurrence. At 1 year, the residual air-bone gap was lower in cases with a partial ossicular reconstruction prosthesis than those with a total ossicular reconstruction prosthesis (16 +/- 9.3 versus 23 +/- 13.7 dB, p < 0.05). The gain in mean air conduction threshold was 21 +/- 12.8 dB in cases of partial ossicular reconstruction prosthesis and 19 +/- 11.3 dB in cases of total ossicular reconstruction prosthesis (not significant). Revision surgery, canal wall-down mastoidectomy, or cholesteatoma yielded poorer functional results.

Conclusion: Partial ossicular reconstruction prosthesis and total ossicular reconstruction prosthesis entirely made of dense hydroxylapatite yielded high rates of air-bone gap reduction and high anatomic stability.

MeSH terms

  • Adult
  • Auditory Threshold
  • Bone Conduction
  • Cholesteatoma, Middle Ear / surgery
  • Chronic Disease
  • Durapatite*
  • Ear Diseases / surgery*
  • Ear Ossicles / surgery*
  • Female
  • Follow-Up Studies
  • Foreign-Body Migration / etiology
  • Humans
  • Male
  • Mastoid / surgery
  • Middle Aged
  • Ossicular Prosthesis* / adverse effects
  • Ossicular Replacement*
  • Otitis Media / surgery
  • Postoperative Period
  • Recurrence
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome

Substances

  • Durapatite