Abstract
This report describes a 72-year-old woman with atrial fibrillation who presented with lower extremity ischemia secondary to thromboembolism. After lower extremity thrombectomy, the patient developed heparin-induced thrombocytopenia with thrombosis (HITT). Her postoperative course was complicated by recurrent supraventricular and ventricular tachycardia, secondary to a mobile thrombus in the right atrium extending into the right ventricle. Because administration of heparin was contraindicated, the patient underwent off-pump right atrial thrombectomy during a brief period of inflow occlusion. Postoperatively, she was placed on lepirudin. Her platelet count normalized without any further thrombotic episodes, and she was discharged on warfarin.
MeSH terms
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Aged
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Atrial Fibrillation / complications
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Atrial Fibrillation / diagnosis
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Cardiac Surgical Procedures / methods
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Cardiopulmonary Bypass
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Combined Modality Therapy
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Female
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Follow-Up Studies
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Heart Atria / physiopathology
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Heart Atria / surgery
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Heparin / adverse effects*
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Heparin / therapeutic use
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Hirudins / analogs & derivatives*
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Humans
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Lower Extremity
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Postoperative Period
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Recombinant Proteins / therapeutic use
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Risk Assessment
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Thrombectomy / methods*
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Thrombocytopenia / chemically induced*
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Thromboembolism / complications
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Thromboembolism / diagnosis
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Thromboembolism / therapy*
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Treatment Outcome
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Venous Thrombosis / complications
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Venous Thrombosis / diagnosis
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Venous Thrombosis / therapy*
Substances
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Hirudins
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Recombinant Proteins
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Heparin
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lepirudin