A zeolite-enzyme combination for biphasic dynamic kinetic resolution of benzylic alcohols

Chem Commun (Camb). 2003 Aug 7:(15):1928-9. doi: 10.1039/b305120j.

Abstract

Acid zeolites like H-Beta are efficient heterogeneous catalysts for racemization of benzylic alcohols in water; by combination of the racemization with an enzymatic kinetic resolution in a two-phase system, enantiomerically pure esters were obtained in high yield via a dynamic kinetic resolution.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzyl Alcohols / chemistry*
  • Catalysis
  • Chemistry, Organic / methods
  • Enzymes / chemistry*
  • Kinetics
  • Solvents / chemistry
  • Stereoisomerism
  • Zeolites / chemistry*

Substances

  • Benzyl Alcohols
  • Enzymes
  • Solvents
  • Zeolites
  • methylphenyl carbinol