Malignant fibrous histiocytoma masquerading as germ cell tumor by producing beta-human chorionic gonadotropin and neuron-specific enolase

Michael Froehner; Franz Theissig; Ralf Konopke; Hans Detlev Saeger; Detlef Ockert

doi:10.1016/s0090-4295(03)00379-0

Malignant fibrous histiocytoma masquerading as germ cell tumor by producing beta-human chorionic gonadotropin and neuron-specific enolase

Urology. 2003 Sep;62(3):551. doi: 10.1016/s0090-4295(03)00379-0.

Authors

Michael Froehner¹, Franz Theissig, Ralf Konopke, Hans Detlev Saeger, Detlef Ockert

Affiliation

¹ Department of Urology, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.

PMID: 12946774
DOI: 10.1016/s0090-4295(03)00379-0

Abstract

Neuron-specific enolase and beta-human chorionic gonadotropin are serum markers frequently found associated with germ cell tumors. To our knowledge, we report the first case of a malignant fibrous histiocytoma producing both markers and discuss the significance of this unusual condition in the differential diagnosis of retroperitoneal tumors.

Publication types

Case Reports

MeSH terms

Biomarkers, Tumor / analysis*
Chorionic Gonadotropin / analysis*
Diagnosis, Differential
Germinoma / diagnosis
Histiocytoma, Benign Fibrous / diagnosis*
Humans
Male
Middle Aged
Phosphopyruvate Hydratase / analysis*
Retroperitoneal Neoplasms / diagnosis*

Substances

Biomarkers, Tumor
Chorionic Gonadotropin
Phosphopyruvate Hydratase