Recent advances in automated solid-phase carbohydrate synthesis: from screening to vaccines

Curr Opin Drug Discov Devel. 2003 Jul;6(4):521-5.

Abstract

The past year has witnessed significant advances in a new technology for the synthesis of complex carbohydrates. Solid-phase methods have been applied to the construction of previously inaccessible carbohydrates. Furthermore, the application of automated solid-phase carbohydrate synthesis is promising. New methods for the synthesis of carbohydrates and potential applications are described in this review.

Publication types

  • Review

MeSH terms

  • Animals
  • Carbohydrates / chemical synthesis*
  • Carbohydrates / immunology
  • Carbohydrates / isolation & purification
  • Drug Evaluation, Preclinical
  • Humans
  • Microcomputers
  • Vaccines / chemical synthesis*

Substances

  • Carbohydrates
  • Vaccines