Preliminary X-ray crystallographic analysis of intercellular adhesion molecule-1

P R Kolatkar; M A Oliveira; M G Rossmann; A H Robbins; S K Katti; H Hoover-Litty; C Forte; J M Greve; A McClelland; N H Olson

doi:10.1016/0022-2836(92)90110-6

Preliminary X-ray crystallographic analysis of intercellular adhesion molecule-1

J Mol Biol. 1992 Jun 20;225(4):1127-30. doi: 10.1016/0022-2836(92)90110-6.

Authors

P R Kolatkar¹, M A Oliveira, M G Rossmann, A H Robbins, S K Katti, H Hoover-Litty, C Forte, J M Greve, A McClelland, N H Olson

Affiliation

¹ Department of Biological Sciences, Purdue University, West Lafayette, IN 47907.

Abstract

Crystals of the two amino-terminal domains of intercellular adhesion molecule-1, the receptor for the major group of human rhinovirus serotypes, diffract to 3.0 A resolution. The crystals are trigonal in space group P3(1)21 or P3(2)21 with cell dimensions of a = b = 55.7 A, c = 166.3 A, with probably six molecules per unit cell.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Antigens, CD / chemistry
Cell Adhesion Molecules / chemistry*
Cell Adhesion Molecules / physiology
Cell Adhesion Molecules / ultrastructure
Humans
Intercellular Adhesion Molecule-1
Microscopy, Electron / methods
Protein Conformation
Receptors, Virus / chemistry*
Receptors, Virus / physiology
Receptors, Virus / ultrastructure
Rhinovirus / physiology*
Rhinovirus / ultrastructure
X-Ray Diffraction / methods

Substances

Antigens, CD
Cell Adhesion Molecules
Receptors, Virus
Intercellular Adhesion Molecule-1