Distribution of hepatitis B virus genotypes in HIV-infected patients with chronic hepatitis B: therapeutic implications

AIDS Res Hum Retroviruses. 2003 Aug;19(8):657-9. doi: 10.1089/088922203322280874.

Abstract

Hepatitis B virus (HBV) genotypes were examined in HIV-infected patients with chronic HBV infection seen in our clinic during 2002. A total of 28 of 1100 individuals (prevalence 2.5%) were found to be HBsAg and HBV-DNA positive. HBV genotypes could be determined in 23 of them. HBV-A was the most common (57%), followed by HBV-D (39%). HBV-A predominated among homosexual men (67%) while HBV-D predominated among intravenous drug users (67%). The presence of serum HBeAg was significantly associated with the HBV-A genotype.

MeSH terms

  • Adult
  • Female
  • Genotype
  • HIV Infections / complications
  • HIV Infections / epidemiology*
  • HIV-1 / isolation & purification*
  • Hepatitis B e Antigens / analysis
  • Hepatitis B virus / genetics*
  • Hepatitis B, Chronic / complications
  • Hepatitis B, Chronic / epidemiology
  • Hepatitis B, Chronic / virology*
  • Homosexuality, Male
  • Humans
  • Male
  • Substance Abuse, Intravenous

Substances

  • Hepatitis B e Antigens