Different expression of tyrosine aminotransferase and serine deydratase in rat livers after partial hepatectomy

Biochem Biophys Res Commun. 1992 Jan 31;182(2):753-9. doi: 10.1016/0006-291x(92)91796-s.

Abstract

Tyrosine aminotransferase activity in rat liver increases during the first 24 hrs after partial hepatectomy with two peaks, one at 10 hrs and another at 18 hrs. This behaviour is due to an increase in TATmRNA synthesis. Expression of serine deydratase is also enhanced during the first 5 hrs after hepatectomy. It is suggested that the enhanced expression of the two genes is due to an increase in hormone incretion particularly glucagon and glucocorticoids.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Hepatectomy
  • Kinetics
  • L-Serine Dehydratase / biosynthesis
  • L-Serine Dehydratase / genetics
  • L-Serine Dehydratase / metabolism*
  • Liver / enzymology*
  • Liver Regeneration*
  • Male
  • Poly A / genetics
  • Poly A / isolation & purification
  • RNA / genetics
  • RNA / isolation & purification
  • RNA, Messenger / metabolism
  • Rats
  • Rats, Inbred Strains
  • Time Factors
  • Tyrosine Transaminase / biosynthesis
  • Tyrosine Transaminase / genetics
  • Tyrosine Transaminase / metabolism*

Substances

  • RNA, Messenger
  • Poly A
  • RNA
  • Tyrosine Transaminase
  • L-Serine Dehydratase