Protein prenylation: key to ras function and cancer intervention?

Cell Growth Differ. 1992 Jul;3(7):461-9.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Alkyl and Aryl Transferases*
  • Amino Acid Sequence
  • Fungal Proteins / metabolism
  • GTP-Binding Proteins / metabolism
  • Humans
  • Lovastatin / analogs & derivatives
  • Lovastatin / pharmacology
  • Lovastatin / therapeutic use
  • Mevalonic Acid / metabolism
  • Molecular Sequence Data
  • Neoplasm Proteins / metabolism
  • Neoplasms / drug therapy
  • Polyisoprenyl Phosphates / metabolism
  • Protein Processing, Post-Translational* / drug effects
  • Proto-Oncogene Proteins p21(ras) / metabolism*
  • Proto-Oncogene Proteins p21(ras) / physiology
  • Saccharomyces cerevisiae / enzymology
  • Saccharomyces cerevisiae / genetics
  • Transferases / metabolism
  • ras Proteins*

Substances

  • Fungal Proteins
  • Neoplasm Proteins
  • Polyisoprenyl Phosphates
  • mevastatin
  • Lovastatin
  • Transferases
  • Alkyl and Aryl Transferases
  • geranylgeranyltransferase type-I
  • p21(ras) farnesyl-protein transferase
  • GTP-Binding Proteins
  • HRAS protein, human
  • Proto-Oncogene Proteins p21(ras)
  • ras Proteins
  • Mevalonic Acid