We report the case of a 26-year-old woman who underwent mitral valvuloplasty during the 23rd week of gestation, following an episode of pulmonary edema. Dilation, performed without complications, increased mitral valve area from 0.9 to 1.8 cm2, cardiac output from 4.8 to 5.9 l/min, and decreased mean transvalvular gradient from 13.2 to 5 mmHg. The patient delivered spontaneously a full-term normal baby. Echocardiographic evaluation at 6 months confirmed the persistency of procedure's good outcome. According to some Authors and to our results it can be inferred that mitral valvuloplasty is a feasible and effective treatment for critical mitral stenosis during pregnancy.