Glomerulonephritis associated with Robertsonian translocation t(13;14)

Nephron. 1992;62(2):220-3. doi: 10.1159/000187036.

Abstract

We report the first case of glomerulonephritis associated with Robertsonian translocation t(13;14) in a 18-year-old female. The renal biopsy revealed mesangial proliferative glomerulonephritis with mesangial IgG and C3 deposits. The patient also has congenital absence of ovaries and an underdeveloped uterus. Our report suggests that renal abnormalities may be found in patients with Robertsonian translocation.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Chromosomes, Human, Pair 13*
  • Chromosomes, Human, Pair 14*
  • Complement C3 / metabolism
  • Female
  • Glomerular Mesangium / immunology
  • Glomerular Mesangium / pathology
  • Glomerulonephritis, Membranoproliferative / genetics*
  • Glomerulonephritis, Membranoproliferative / immunology
  • Glomerulonephritis, Membranoproliferative / pathology
  • Humans
  • Immunoglobulin G / metabolism
  • Karyotyping
  • Ovary / abnormalities
  • Translocation, Genetic*

Substances

  • Complement C3
  • Immunoglobulin G