Abstract
Anemia and hepatosplenomegaly are common reasons for referring a child to a pediatric hematologist or oncologist. Among the many causes for these findings is severe rickets, which has been shown to be associated with secondary myelofibrosis and myeloid metaplasia. The authors present the case of an infant with severe rickets and secondary myelofibrosis and review the differential diagnosis of hepatosplenomegaly from the viewpoint of the pediatric hematologist/oncologist.
MeSH terms
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Anemia / complications*
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Anemia / diagnosis
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Anemia / pathology
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Calcitriol / therapeutic use
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Diagnosis, Differential
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Hepatomegaly / complications*
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Hepatomegaly / diagnosis
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Hepatomegaly / pathology
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Humans
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Infant
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Male
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Primary Myelofibrosis / complications*
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Primary Myelofibrosis / diagnosis
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Primary Myelofibrosis / pathology
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Rickets / complications*
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Rickets / diagnosis*
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Rickets / drug therapy
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Rickets / pathology
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Splenomegaly / complications*
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Splenomegaly / diagnosis
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Splenomegaly / pathology