Rheumatoid nodulosis: a puzzling variant of rheumatoid arthritis

Clin Rheumatol. 1992 Sep;11(3):396-401. doi: 10.1007/BF02207201.

Abstract

Four patients with rheumatoid nodulosis are here described, together with a review of cases reported to date in the literature. This particular variant of rheumatoid arthritis (RA) is characterized by the presence of subcutaneous rheumatoid nodules, scanty or absent systemic manifestations and a clinically benign course. Joint involvement appears more commonly as palindromic rheumatism, although patients with arthralgia episodes alone and others with chronic polyarthritis have been described. Seldom reported up to now, a consideration of this entity may help to avoid diagnostic pitfalls and the use of aggressive therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Arthritis, Rheumatoid / diagnostic imaging
  • Arthritis, Rheumatoid / genetics*
  • Arthritis, Rheumatoid / pathology
  • Female
  • Genetic Variation
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Radiography
  • Rheumatoid Nodule / diagnosis*
  • Rheumatoid Nodule / diagnostic imaging
  • Rheumatoid Nodule / pathology