Medical students in their 1st year (N=71) were assessed prior to starting training and at year's end. Coping styles reported at baseline were strongly related to coping styles at the end of the year. Students' physical health and psychological well-being declined over the course of the year. The greater the students' use of both problem-focused coping and approach emotion-focused coping, the less their physical health deteriorated. Psychological well-being at year's end was more strongly related to baseline functioning, and coping style did not predict change. This study demonstrated the utility of measuring coping style and the predictive ability of coping on physical health in a healthy sample.