Avascular necrosis of the femoral head in a HIV-1 infected patient receiving lopinavir/ritonavir

Marco Bongiovanni; Elisabetta Chiesa; Agostino Riva; Antonella d'Arminio Monforte; Teresa Bini

doi:10.1016/j.ijantimicag.2003.05.006

Avascular necrosis of the femoral head in a HIV-1 infected patient receiving lopinavir/ritonavir

Int J Antimicrob Agents. 2003 Dec;22(6):630-1. doi: 10.1016/j.ijantimicag.2003.05.006.

Authors

Marco Bongiovanni¹, Elisabetta Chiesa, Agostino Riva, Antonella d'Arminio Monforte, Teresa Bini

Affiliation

¹ Institute of Infectious Diseases and Tropical Medicine, Luigi Sacco Hospital, University of Milan, Via G.B. Grassi 74, 20157 Milan, Italy. marco.bongiovanni@unimi.it

PMID: 14659664
DOI: 10.1016/j.ijantimicag.2003.05.006

Abstract

The wide use of protease inhibitors (PI) as part of a highly active antiretroviral (HAART) regimen is associated with the development of several side effects. Among these, the development of avascular necrosis (AVN) of the bone is being reported more frequently and it has been related both to the use of PI and to HIV-1 infection itself. We report here a case of AVN of the bone in a patient taking the new PI lopinavir (LPV)/ritonavir (RTV) as part of a HAART regimen.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antiretroviral Therapy, Highly Active / adverse effects*
Femur Head Necrosis / etiology*
HIV Infections / complications
HIV Infections / drug therapy*
HIV-1
Humans
Lopinavir
Male
Pyrimidinones / adverse effects*
Ritonavir / adverse effects*

Substances

Pyrimidinones
Lopinavir
Ritonavir