Comparison of Campylobacter jejuni isolates implicated in Guillain-Barré syndrome and strains that cause enteritis by a DNA microarray

Edward E Leonard 2nd; Lucy S Tompkins; Stanley Falkow; Irving Nachamkin

doi:10.1128/IAI.72.2.1199-1203.2004

Comparison of Campylobacter jejuni isolates implicated in Guillain-Barré syndrome and strains that cause enteritis by a DNA microarray

Infect Immun. 2004 Feb;72(2):1199-203. doi: 10.1128/IAI.72.2.1199-1203.2004.

Authors

Edward E Leonard 2nd¹, Lucy S Tompkins, Stanley Falkow, Irving Nachamkin

Affiliation

¹ Department of Microbiology and Immunology, Stanford University, Stanford, California 94305, USA.

Abstract

We asked whether Campylobacter jejuni isolated from patients with Guillain-Barré syndrome (GBS) differ from isolates isolated from patients with uncomplicated gastrointestinal infection using DNA microarray analysis. We found that specific GBS genes or regions were not identified, and microarray analysis confirmed significant genomic heterogeneity among the isolates.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Campylobacter jejuni / genetics*
Enteritis / microbiology*
Genetic Variation
Genome, Bacterial*
Guillain-Barre Syndrome / microbiology*
Humans
Oligonucleotide Array Sequence Analysis / methods*

Abstract

Publication types

MeSH terms

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