Haplotype and cancer risk analysis of two common mutations, BRCA1 4184del4 and BRCA2 2157delG, in high risk northwest England breast/ovarian families

J Med Genet. 2004 Feb;41(2):e21. doi: 10.1136/jmg.2003.012104.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • BRCA1 Protein / genetics
  • BRCA2 Protein / genetics
  • Breast Neoplasms / epidemiology
  • Breast Neoplasms / genetics*
  • Breast Neoplasms, Male / genetics*
  • DNA, Neoplasm / genetics
  • England / epidemiology
  • Female
  • Founder Effect
  • Genes, BRCA1*
  • Genes, BRCA2*
  • Haplotypes / genetics*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Mutation / genetics*
  • Ovarian Neoplasms / genetics*
  • Pedigree
  • Risk Assessment
  • Sequence Deletion / genetics*

Substances

  • BRCA1 Protein
  • BRCA2 Protein
  • DNA, Neoplasm