Comparison between two different assays for measurements of allergen-specific IgE and skin prick test in the diagnosis of insect venom allergy

Allergy. 1992 Oct;47(5):495-7. doi: 10.1111/j.1398-9995.1992.tb00671.x.

Abstract

Forty-one patients stung by wasp and 29 by bee were evaluated by comparing the correlation between skin prick test (SPT), Phadebas radioallergosorbent test (P-RAST) and Magic Lite SQ Specific IgE assay (LIA). All patients had had a systemic reaction to insect sting. In the patients stung by bee we found agreement between SPT and P-RAST, and SPT and LIA. Similarly, there were no significant differences in sensitivity between P-RAST and LIA (p > 0.05). In patients stung by wasp, SPT was found to be more sensitive than P-RAST. There were no differences between SPT and LIA or between P-RAST and LIA.

Publication types

  • Comparative Study

MeSH terms

  • Allergens / analysis*
  • Bee Venoms / immunology*
  • Humans
  • Hypersensitivity / diagnosis*
  • Hypersensitivity / immunology
  • Immunoassay / methods*
  • Immunoglobulin E / analysis*
  • Insect Bites and Stings / immunology*
  • Luminescent Measurements
  • Radioallergosorbent Test
  • Sensitivity and Specificity
  • Skin Tests
  • Wasp Venoms / immunology*

Substances

  • Allergens
  • Bee Venoms
  • Wasp Venoms
  • Immunoglobulin E