Tumour vaccine associated lymphadenopathy and false positive positron emission tomography scan changes

Br J Radiol. 2004 Jan;77(913):74-5. doi: 10.1259/bjr/19323466.

Abstract

A patient receiving intradermal injections of vaccine directed towards carcinoembryonic antigen-bearing metastases from colorectal cancer showed uptake of 18F-fluorodeoxyglucose in local draining lymph nodes during the course of treatment. This appearance should be considered as a possible false positive in patients undergoing such treatment who are being investigated with PET scans.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / secondary
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Axilla
  • Cancer Vaccines / adverse effects*
  • Carcinoembryonic Antigen / metabolism
  • Colorectal Neoplasms*
  • Humans
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / secondary
  • Lymphatic Diseases / chemically induced*
  • Male
  • Middle Aged
  • Tomography, Emission-Computed

Substances

  • Cancer Vaccines
  • Carcinoembryonic Antigen