A prospective epidemiological survey of candidaemia in Sweden

Scand J Infect Dis. 2004;36(1):52-5. doi: 10.1080/00365540310017447.

Abstract

A prospective epidemiological survey of candidaemia was performed in central Sweden from January 1998 to December 1999. In total, 191 episodes were reported with an overall rate of 0.32/1000 admissions. Candida albicans was identified in 128 cases (67%), followed by Candida glabrata in 30 (15.7%) and Candida parapsilosis in 14 (7.3%). Predisposing factors included surgery (31.4%), intensive care (18.8%), solid tumour or haematological malignancy (15.7%), and foetal immaturity (15.7%). Non-albicans Candida species were more prevalent among patients with haematological malignancies (56%), compared to surgical (30%) and ICU patients (19%). The crude mortality rate of candidaemia was 31%. The highest mortality rate was observed in patients with haematological malignancies (41.2%), age > 70 y (41%), surgery (38.5%) and infections with > 1 Candida species (40%) or C. glabrata (38%).

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Antifungal Agents / therapeutic use
  • Candidiasis / diagnosis
  • Candidiasis / drug therapy
  • Candidiasis / epidemiology*
  • Child
  • Child, Preschool
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Female
  • Fungemia / diagnosis
  • Fungemia / drug therapy
  • Fungemia / epidemiology*
  • Health Surveys
  • Hospitalization / statistics & numerical data
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Intensive Care Units
  • Male
  • Middle Aged
  • Prognosis
  • Prospective Studies
  • Risk Assessment
  • Sex Distribution
  • Survival Rate
  • Sweden / epidemiology

Substances

  • Antifungal Agents