Vascular anastomosing by gluing--an experimental study

Thorac Cardiovasc Surg. 2004 Feb;52(1):6-9. doi: 10.1055/s-2004-815797.

Abstract

Background: Performing anastomoses by stitching is very time-consuming. We therefore looked for an alternative technique and used a relatively new surgical adhesive.

Methods: Ten anastomoses between the aorta and a prosthesis were performed on five pigs (Deutsche Landrasse) using surgical glue (BioGlue). The proximal anastomoses between the abdominal aorta and the prostheses were performed end-to-side just below the renal arteries, the distal anastomoses in an end-to-end fashion just above the iliac bifurcation. The aorta between the anastomoses was ligated and resected. The animals were sacrificed between one week and up to four months after operation and anastomoses were analysed by angiography, CT angiography, angioscopy, and histology.

Results: Angiography and CT angiography revealed that all anastomoses were patent. No aneurysms were found at the site of anastomoses. No haematomas were detected. Angioscopy revealed well-healed connections between the original aorta and the prosthesis.

Conclusions: We could demonstrate that anastomoses between the aorta and a prosthesis can be performed safely using a surgical adhesive. Further investigations of these anastomoses, especially over the long term, using calcified aortas, are necessary.

MeSH terms

  • Adhesives / pharmacology*
  • Anastomosis, Surgical
  • Animals
  • Aorta, Abdominal / diagnostic imaging
  • Aorta, Abdominal / physiopathology
  • Aorta, Abdominal / surgery
  • Aortic Aneurysm, Abdominal / diagnostic imaging
  • Aortic Aneurysm, Abdominal / physiopathology
  • Aortic Aneurysm, Abdominal / surgery
  • Aortic Dissection / diagnostic imaging
  • Aortic Dissection / physiopathology
  • Aortic Dissection / surgery
  • Blood Vessel Prosthesis
  • Female
  • Models, Animal
  • Models, Cardiovascular
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / etiology
  • Swine
  • Tomography, X-Ray Computed
  • Tunica Media / diagnostic imaging
  • Tunica Media / physiopathology
  • Tunica Media / surgery
  • Vascular Patency / physiology
  • Vascular Surgical Procedures*

Substances

  • Adhesives