A convenient procedure for bismuth-mediated Barbier-type allylation of aldehydes in water containing fluoride ions

Org Biomol Chem. 2004 Mar 21;2(6):935-8. doi: 10.1039/b400179f. Epub 2004 Feb 25.

Abstract

A new and convenient procedure for synthesis of homoallylic alcohols in generally good to excellent yields has been developed. The bismuth-mediated Barbier-type allylation of aldehydes (aromatic, aliphatic, alicyclic and heterocyclic) with allyl bromide has been carried out smoothly in water in the presence of fluoride ions.