[Paradox: when a prothrombotic disorder is responsible for an upper gastrointestinal bleeding. Case report of hepatoportal sclerosis]

Rev Med Liege. 2004 Jan;59(1):32-4.
[Article in French]

Abstract

Variceal bleeding is frequently the initial presentation of a previously unknown cirrhosis. Portal hypertension and its complications without liver cirrhosis should raise the possibility of presinusoidal portal hypertension, and the diagnosis of hepatoportal sclerosis. These patients need to be investigated for coagulation disorders. A hypercoagulable state is often associated. Risks and benefits of anticoagulation should be further investigated in these patients.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Anticoagulants / adverse effects
  • Anticoagulants / therapeutic use
  • Biopsy
  • Blood Coagulation Tests
  • Esophageal and Gastric Varices / etiology*
  • Esophageal and Gastric Varices / therapy
  • Fibrosis / complications
  • Gastrointestinal Hemorrhage / etiology*
  • Gastrointestinal Hemorrhage / therapy
  • Humans
  • Hypertension, Portal / complications*
  • Hypertension, Portal / diagnosis
  • Hypertension, Portal / therapy
  • Liver Cirrhosis / complications*
  • Liver Cirrhosis / diagnosis
  • Liver Cirrhosis / therapy
  • Male
  • Melena / etiology
  • Portal System
  • Protein C Deficiency / congenital*
  • Protein C Deficiency / diagnosis
  • Protein C Deficiency / therapy
  • Protein S Deficiency / congenital*
  • Protein S Deficiency / diagnosis
  • Protein S Deficiency / therapy
  • Sclerotherapy
  • Thrombocytopenia / congenital*
  • Thrombocytopenia / diagnosis
  • Thrombocytopenia / therapy

Substances

  • Anticoagulants