Antimicrobial susceptibility and mechanisms of resistance to quinolones and beta-lactams in Acinetobacter genospecies 3

A Ribera; F Fernández-Cuenca; A Beceiro; G Bou; L Martínez-Martínez; A Pascual; J M Cisneros; J Rodríguez-Baño; J Pachón; J Vila; Spanish Group for Nosocomial Infection

doi:10.1128/AAC.48.4.1430-1432.2004

Antimicrobial susceptibility and mechanisms of resistance to quinolones and beta-lactams in Acinetobacter genospecies 3

Antimicrob Agents Chemother. 2004 Apr;48(4):1430-2. doi: 10.1128/AAC.48.4.1430-1432.2004.

Authors

A Ribera¹, F Fernández-Cuenca, A Beceiro, G Bou, L Martínez-Martínez, A Pascual, J M Cisneros, J Rodríguez-Baño, J Pachón, J Vila; Spanish Group for Nosocomial Infection

Affiliation

¹ Servei de Microbiologia, Institut Clínic Infeccions i Immunologia, IDIBAPS, Hospital Clínic, 08036 Barcelona, Spain.

Abstract

Antimicrobial susceptibility was determined in 15 epidemiologically unrelated clinical isolates of Acinetobacter genospecies 3. Moreover, the mechanisms of resistance to some beta-lactam antibiotics may be associated with the presence of a chromosomal cephalosporinase, AmpC, and the resistance to quinolones related to mutations in the gyrA and parC genes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acinetobacter / drug effects*
Acinetobacter / genetics*
Anti-Bacterial Agents / pharmacology*
Anti-Infective Agents / pharmacology*
Genes, Bacterial / genetics
Microbial Sensitivity Tests
Quinolones / pharmacology*
Reverse Transcriptase Polymerase Chain Reaction
beta-Lactams / pharmacology*

Substances

Anti-Bacterial Agents
Anti-Infective Agents
Quinolones
beta-Lactams