Abstract
Factors associated with failure of antifungal therapy were examined in 42 cancer patients with fusariosis (1987-1997). Thirty-six patients (86%) had leukemia and 39 (93%) were neutropenic. Disseminated infection was the most common presentation. The majority (83%) received amphotericin B-based therapy. Thirty patients (71%) failed therapy. No patient with persistent neutropenia responded.
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Female
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Fusarium*
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Hematologic Neoplasms / complications*
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Hematologic Neoplasms / microbiology
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Humans
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Leukocyte Count
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Male
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Middle Aged
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Mycoses / complications*
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Mycoses / diagnosis*
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Mycoses / drug therapy
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Mycoses / immunology
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Neutropenia / complications
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Neutropenia / microbiology
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Neutrophils / cytology
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Neutrophils / physiology*
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Treatment Outcome