Cytomegalovirus Retinitis in infancy

Eye (Lond). 2004 Apr;18(4):389-92. doi: 10.1038/sj.eye.6700696.

Abstract

Purpose: To describe the presentation of cytomegalovirus retinitis (CMVR) in a series of infants.

Methods: Immunocompromised infants with either HIV or systemic cytomegalovirus (CMV) were examined for CMVR. Ocular involvement was recorded and monitored by digital imaging.

Results: Five infants were detected to have CMVR. All the infants demonstrated changes within the macula. One infant progressed from a fine granular pattern to fulminant CMVR.

Conclusion: Infants under a year with CMVR have a predilection for the disease to present at the macula, in contrast to the presentation in adults, which tends to involve more peripheral parts of the retina.

Publication types

  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections / immunology
  • AIDS-Related Opportunistic Infections / pathology
  • AIDS-Related Opportunistic Infections / virology
  • Cytomegalovirus Retinitis / immunology
  • Cytomegalovirus Retinitis / pathology*
  • Cytomegalovirus Retinitis / virology
  • Female
  • Humans
  • Immunocompromised Host
  • Infant
  • Infant, Newborn
  • Macula Lutea / pathology
  • Male
  • Viral Load