Serum interleukin-6 in patients with adrenal tumors

Bull Exp Biol Med. 2004 Mar;137(3):273-5. doi: 10.1023/b:bebm.0000031568.91551.3b.

Abstract

The mean blood content of interleukin-6 in patients with adrenal tumors was much higher than in healthy donors. No correlations were revealed between interleukin-6 level, patients sex and age, stage and duration of the disease. Interleukin-6 concentration was maximum in patients with adrenocortical cancer. A negative correlation was found between interleukin-6 level and blood cortisol concentration in patients with cortisol-producing adenoma. In patients with aldosterone-producing adenoma, interleukin-6 level tended to correlate negatively with plasma renin activity.

MeSH terms

  • Adenoma / immunology
  • Adenoma / metabolism
  • Adrenal Cortex Neoplasms / immunology
  • Adrenal Cortex Neoplasms / metabolism
  • Adrenal Gland Neoplasms / immunology*
  • Adrenal Gland Neoplasms / metabolism
  • Adult
  • Aged
  • Aldosterone / biosynthesis
  • Case-Control Studies
  • Female
  • Humans
  • Hydrocortisone / biosynthesis
  • Hydrocortisone / blood
  • Interleukin-6 / blood*
  • Male
  • Middle Aged
  • Renin / blood

Substances

  • Interleukin-6
  • Aldosterone
  • Renin
  • Hydrocortisone