Breast-conserving therapy and sentinel lymph node biopsy are feasible in cancer patients with previous implant breast augmentation

Am J Surg. 2004 Aug;188(2):122-5. doi: 10.1016/j.amjsurg.2003.12.062.

Abstract

Background: Breast-conserving therapy (BCT) is reported to result in a significant rate of complications and local recurrences in patients with prior implant breast augmentation. The role of sentinel lymph node (SLN) biopsy in these patients is unknown.

Methods: Retrospective review of patients with prior breast augmentation treated with BCT or SLN biopsy.

Results: Nineteen breast cancers were treated with BCT. Of 17 breasts undergoing adjuvant radiotherapy, 11 (64.7%) retained favorable aesthetic results. Of 9 subpectoral implants, capsular contracture developed in only 1 (11.1%). During follow-up (median 3 years), 1 local recurrence (5.3%) occurred in a patient who refused adjuvant radiotherapy and systemic therapy. Eleven patients underwent SLN biopsy with an identification rate of 100% and a false-negative rate of 0%.

Conclusions: Breast-conserving therapy inclusive of radiotherapy after implant breast augmentation produced acceptable cosmetic results in nearly two-thirds of patients. Sentinel lymph node mapping in the setting of prior implant augmentation was highly successful and accurate.

MeSH terms

  • Adult
  • Aged
  • Breast Implants*
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery*
  • Female
  • Humans
  • Mastectomy, Segmental*
  • Middle Aged
  • Radiotherapy Dosage
  • Radiotherapy, Adjuvant
  • Retrospective Studies
  • Sentinel Lymph Node Biopsy*