Variability in nomenclature used for nevi with architectural disorder and cytologic atypia (microscopically dysplastic nevi) by dermatologists and dermatopathologists

J Cutan Pathol. 2004 Sep;31(8):523-30. doi: 10.1111/j.0303-6987.2004.00216.x.

Abstract

Background: Although a nevus with the microscopic features of a "dysplastic nevus" is commonly seen, the nomenclature used to describe such a lesion has been thought to be inconsistent. A 1992 National Institutes of Health (NIH) Consensus Conference sought to unify nomenclature and suggested that the term "nevus with architectural disorder" be used along with a comment on melanocytic atypia.

Methods: We performed a cross-sectional mail survey to determine preferred terminology as well as the level of adherence to the NIH-recommended nomenclature. All 856 active members of the American Society of Dermatopathology (ASDP) and 1100 (13.0%) of the 8471 active members of the American Academy of Dermatology (AAD) were surveyed.

Results: Five hundred and thirty-three ASDP members and 483 AAD members who fulfilled eligibility criteria completed the questionnaire. The term "dysplastic nevus" was favored by the largest number of responders (favored by 39.1% of ASDP members and 62.3% of AAD members), while the 1992 NIH Consensus Conference-recommended terminology was the second most popular term (25.3% of ASDP and 15.1% of AAD members). Dermatopathologists (OR = 1.9, p = 0.0001) and those who had dual training in dermatology and dermatopathology (OR = 1.6, p = 0.02 for ASDP members; OR = 2.3, p = 0.02 for AAD members) were more likely to adhere to the 1992 NIH Consensus Conference nomenclature.

Conclusions: Despite attempts to unify nomenclature for microscopically dysplastic nevi through the NIH Consensus Conference, wide variation in terminology persists.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Consensus Development Conferences as Topic
  • Cross-Sectional Studies
  • Dermatology / methods*
  • Dermatology / standards
  • Dysplastic Nevus Syndrome / classification*
  • Dysplastic Nevus Syndrome / pathology
  • Female
  • Humans
  • Male
  • Pathology, Clinical / methods*
  • Pathology, Clinical / standards
  • Practice Guidelines as Topic
  • Skin Neoplasms / classification*
  • Skin Neoplasms / pathology
  • Societies, Medical
  • Surveys and Questionnaires
  • Terminology as Topic*
  • United States