[Predictors associated with clinical deterioration in SARS patients]

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2003 Sep;17(3):222-4.
[Article in Chinese]

Abstract

Background: To study the predictive factors associated with clinical deterioration in SARS patients.

Methods: The clinical data of 60 SARS patients were analyzed by logistic regression and Cox's proportional hazards analysis.

Results: In logistic regression models, both older age (P=0.009) and severe lymphopenia (P=0.004) were significant predictors of clinical deterioration. In Cox's proportional hazard models, severe lymphopenia was significant predictor associated with prolongation of stay in hospital.

Conclusion: Older age and severe lymphopenia seem to be statistically significant for predicting the clinical deterioration in SARS patients.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Disease Progression
  • Female
  • Humans
  • Logistic Models
  • Lymphopenia / virology
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prognosis
  • Proportional Hazards Models
  • Random Allocation
  • Severe Acute Respiratory Syndrome / complications
  • Severe Acute Respiratory Syndrome / diagnosis*
  • Severe Acute Respiratory Syndrome / immunology*
  • Severe Acute Respiratory Syndrome / virology
  • Severe acute respiratory syndrome-related coronavirus