Liver transplantation in Medellin, Colombia: initial experience

Transplant Proc. 2004 Jul-Aug;36(6):1677-80. doi: 10.1016/j.transproceed.2004.06.020.

Abstract

Objective: The goal of this article is to present the experience of a new liver transplant team.

Materials and methods: This review includes all patients who received a liver transplant between March 15, 2000 and March 15, 2003.

Results: We performed 87 transplantations on 84 patients; 39 were females and 45 were males of average age 43.6 years, including 6 children. The majority of the patients were from Colombia with time on the waiting list of less than 1 month. The average donor age was 26.7 years. The preservation solutions included Wisconsin, HTK-Brettschneider (Custodiol), and Corpaúl (similar to Henn-Ross). In this study, 95.4% were whole livers, with 97.7% using the piggyback method. We placed 23 arterial grafts and 2 venous grafts for vascular reconstructions; 95.4% were duct-to-duct anastomosis (95.4%). Among the cohort, 8.3% experienced acute rejection and 1.2% experienced chronic rejection. Two patients required retransplantation due to hepatic artery thrombosis with biliary tree necrosis.

Conclusions: We consider that we have passed the crisis of beginning a new program with a reduction in postoperative complications and improving patient and graft survival. At present, we are a center that performs liver transplantations in adults and children, with a good organ donation culture in our city that allows us to offer a waiting time on the list less than one month. Neither a veno-venous bypass nor a T-tube were necessary for our cases. We also have developed a new, less expensive form of perfusing the liver in the donor.

MeSH terms

  • Adult
  • Cause of Death
  • Child
  • Colombia
  • Graft Survival / immunology
  • Humans
  • Liver Transplantation / immunology
  • Liver Transplantation / methods
  • Liver Transplantation / mortality
  • Liver Transplantation / statistics & numerical data*
  • Postoperative Complications / classification
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Survival Analysis
  • Tissue Donors / statistics & numerical data