Abstract
Vancomycin-resistant Enterococcus faecium (VREFM) is becoming a threatening pathogen. We identified a gene called DD1.5K by differential display-PCR, which was preferentially expressed in the bloodstream isolates of VREFM. Due to its amino acid similarity to transfer complex protein, trsE, and tissue-specific expression, this gene may be involved in virulence of VREFM.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adaptation, Physiological
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Amino Acid Sequence
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Animals
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Bacterial Proteins / biosynthesis
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Bacterial Proteins / genetics*
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Blood / microbiology*
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Chickens / blood
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Chickens / microbiology
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DNA, Bacterial / chemistry
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DNA, Bacterial / isolation & purification
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Enterococcus faecium / genetics*
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Enterococcus faecium / growth & development
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Enterococcus faecium / isolation & purification
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Enterococcus faecium / metabolism
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Gene Expression Profiling / methods
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Gene Expression Regulation, Bacterial*
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Genes, Bacterial
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Gram-Positive Bacterial Infections / microbiology
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Humans
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Molecular Sequence Data
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Sequence Analysis, DNA
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Vancomycin Resistance / genetics
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Virulence Factors / genetics*
Substances
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Bacterial Proteins
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DNA, Bacterial
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Virulence Factors