Non-Hodgkin lymphoma in a child with Williams syndrome

Cancer Genet Cytogenet. 2004 Oct 1;154(1):86-8. doi: 10.1016/j.cancergencyto.2004.02.004.

Abstract

Non-Hodgkin lymphoma in an 8-year-old boy with Williams syndrome is reported. Molecular DNA analysis showed a maternal deletion at 7q11.23, the locus of elastin and several other genes, including the BCL7B gene, involved in early development. To our knowledge, this is the second reported case of a lymphoma in a Williams syndrome patient and the first in a child.

Publication types

  • Case Reports

MeSH terms

  • Burkitt Lymphoma / etiology
  • Burkitt Lymphoma / genetics*
  • Child
  • Chromosome Deletion
  • Chromosomes, Human, Pair 7
  • Humans
  • Ileal Neoplasms / etiology
  • Ileal Neoplasms / genetics
  • Male
  • Proteins / genetics
  • Williams Syndrome / complications
  • Williams Syndrome / genetics*

Substances

  • BCL7B protein, human
  • Proteins