Abstract
Real-time 3-dimensional echocardiography was performed in 10 patients with obstructive hypertrophic cardiomyopathy (HC) before and after myectomy and in 6 controls. The exact location of systolic anterior motion of the mitral leaflet was shown in all patients with HC with a predominant involvement of the medial portion in 4 patients and the middle portion in 6 patients. The smallest area of the left ventricular outflow tract was significantly smaller in patients with HC than in controls (1.4 +/- 0.7 vs 5.1 +/- 1.2 cm(2), p <0.01), significantly increased after myectomy (4.8 +/- 1.8 cm2, p <0.01) and was associated with a reduction of the pressure gradient at rest from 63 +/- 41 to 15 +/- 5 mm Hg (p <0.01).
Publication types
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Comparative Study
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Evaluation Study
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adult
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Aorta / diagnostic imaging
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Aorta / physiopathology
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Cardiac Catheterization
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Cardiac Surgical Procedures*
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Cardiomyopathy, Hypertrophic / diagnostic imaging*
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Cardiomyopathy, Hypertrophic / physiopathology
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Cardiomyopathy, Hypertrophic / surgery*
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Computer Systems*
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Echocardiography
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Echocardiography, Doppler
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Echocardiography, Three-Dimensional*
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Female
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Heart Septum / diagnostic imaging
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Heart Septum / physiopathology
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Heart Ventricles / diagnostic imaging
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Heart Ventricles / physiopathology
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Humans
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Male
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Middle Aged
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Mitral Valve Insufficiency / diagnostic imaging
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Mitral Valve Insufficiency / physiopathology
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Mitral Valve Insufficiency / surgery
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Systole / physiology
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Treatment Outcome
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Ventricular Outflow Obstruction / diagnostic imaging
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Ventricular Outflow Obstruction / physiopathology
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Ventricular Outflow Obstruction / surgery