Abstract
Chiral aziridine sulfides and disulfides were synthesized from readily available and inexpensive R-cysteine by a Mitsunobu reaction; their application in the addition of diethylzinc to aldehydes provides secondary alcohols with up to 99% ee and S-configuration.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alcohols / chemical synthesis
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Aldehydes / chemistry*
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Aziridines / chemistry*
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Catalysis
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Molecular Structure
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Organometallic Compounds / chemistry*
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Stereoisomerism
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Sulfides / chemistry*
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Zinc / chemistry*
Substances
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Alcohols
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Aldehydes
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Aziridines
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Organometallic Compounds
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Sulfides
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aziridine
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Zinc