The management of advanced stage ovarian cancer was deeply modified during last years. The standard treatment of advanced stage ovarian cancer in 2004 remains the initial surgery (in order to obtain ideally a total resection of all macroscopic disease) followed by adjuvant chemotherapy (6 courses of platinum based chemotherapy). But in patients with massive spread, interval debulking surgery (performed after 3 or 4 courses of neo-adjuvant chemotherapy) is becoming an interesting option (and perhaps will become a standard management). This treatment is actually studied in randomized trials.