The co-expression of PML/RAR alpha and AML1/ETO fusion genes is associated with ATRA resistance

Br J Haematol. 2005 Feb;128(3):407-9. doi: 10.1111/j.1365-2141.2004.05343.x.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Core Binding Factor Alpha 2 Subunit
  • Drug Resistance, Neoplasm / genetics*
  • Female
  • Humans
  • Karyotyping
  • Leukemia, Myeloid / genetics*
  • Leukemia, Promyelocytic, Acute / genetics
  • Middle Aged
  • Oncogene Proteins, Fusion / genetics*
  • RUNX1 Translocation Partner 1 Protein
  • Receptors, Retinoic Acid / genetics
  • Retinoic Acid Receptor alpha
  • Transcription Factors / genetics
  • Tretinoin / therapeutic use*

Substances

  • AML1-ETO fusion protein, human
  • Antineoplastic Agents
  • Core Binding Factor Alpha 2 Subunit
  • Oncogene Proteins, Fusion
  • RARA protein, human
  • RUNX1 Translocation Partner 1 Protein
  • Receptors, Retinoic Acid
  • Retinoic Acid Receptor alpha
  • Transcription Factors
  • Tretinoin