Comparison of stiffness and failure load of two cervical spine fixation techniques in an in vitro human model

J Spinal Disord Tech. 2005 Feb:18 Suppl:S115-8. doi: 10.1097/01.bsd.0000132288.65702.6e.

Abstract

Objective: Recently, an unpaired threaded cage has been introduced as a fusion device for the cervical spine. No biomechanical comparison of a stand-alone single interbody threaded cage to a standard plated Smith-Robinson construct has been reported. Accordingly, an in vitro biomechanical comparison of a single threaded cylindrical interbody fusion cage versus a plated Smith-Robinson cervical discectomy and fusion construct was conducted to establish whether a single cylindrical interbody cage in the cervical spine would perform mechanically as well as a plated structural interbody graft.

Methods: Six fresh-frozen human cadaveric cervical spines were used for biomechanical testing. Flexion-extension and load-to-failure testing were performed on two single-level discectomy and interbody fusion constructs from each specimen.

Results: Initial range of motion (ROM) was significantly greater for the specimens implanted with a cage than specimens implanted with a structural graft and plate (9.1 degrees +/- 3.7 degrees vs 5.8 degrees +/- 2.4 degrees ; P = 0.040). Initial stiffness in flexion in caged specimens was significantly less than in plated specimens (0.7 +/- 0.3 vs 0.9 +/- 0.3 Nm/ degrees ; P = 0.028). Cage specimens also failed at a significantly lower load than plated specimens (9.8 +/- 3.5 vs 15.8 +/- 4.1 Nm; P = 0.0104).

Conclusions: This study demonstrates that a plated Smith-Robinson cervical discectomy and fusion construct provides greater stiffness and failure load and reduced ROM across operated levels than a single interbody cage construct. Although clinical success may not directly correlate with biomechanical data, these results raise concern regarding the use of a single threaded interbody cage as a stand-alone device for cervical interbody fusion.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bone Plates / standards
  • Cadaver
  • Cervical Vertebrae / pathology
  • Cervical Vertebrae / physiology*
  • Cervical Vertebrae / surgery*
  • Diskectomy / instrumentation
  • Diskectomy / methods
  • Humans
  • Internal Fixators / standards*
  • Postoperative Complications / etiology
  • Postoperative Complications / physiopathology
  • Postoperative Complications / prevention & control
  • Range of Motion, Articular / physiology
  • Spinal Fusion / adverse effects
  • Spinal Fusion / instrumentation*
  • Stress, Mechanical
  • Treatment Failure
  • Weight-Bearing / physiology