The aim of the study: To evaluate the results of treatment in patients with Wilm's' tumor in stage IV at the Gdansk Medical University Centre.
Material and methods: Between 1993 and 2002, 44 children with nephroblastoma were treated according to SI0P 93-01 protocol, in the Department of Paediatrics, Haematology, Oncology and Endocrinology of the Medical University of Gdansk. Stage IV tumour was confirmed in 6 children: 3 boys and 3 girls. Metastases into the lungs were identified in 4 patients, into the lungs and liver in l child and into the right atrium wall in l child.
Results: After preoperative chemotherapy complete regression of metastases was obtained in 3 patients. Partial regression was obtained in 2 patients. In l patient there was no effect of preoperative treatment. In all patients nephroblastoma of intermediate histological risk was diagnosed. Among the 6 analysed patients with stage IV of the disease, 5 children are alive. Time of observation is from 42 to 102 months. 1 child died from treatment complications: necrotising enteritis.