Protein structure topological comparison, discovery and matching service

G M Torrance; D R Gilbert; I Michalopoulos; D W Westhead

doi:10.1093/bioinformatics/bti331

Protein structure topological comparison, discovery and matching service

Bioinformatics. 2005 May 15;21(10):2537-8. doi: 10.1093/bioinformatics/bti331. Epub 2005 Mar 1.

Authors

G M Torrance¹, D R Gilbert, I Michalopoulos, D W Westhead

Affiliation

¹ Bioinformatics Research Centre, Department of Computer Science, University of Glasgow, Glasgow G12 8QQ, UK.

PMID: 15741246
DOI: 10.1093/bioinformatics/bti331

Abstract

We describe a fold level fast protein comparison and motif matching facility based on the TOPS representation of structure. This provides an update to a previous service at the EBI, with a better graph matching with faster results and visualization of both the structures being compared against and the common pattern of each with the target domain.

Availability: Web service at http://balabio.dcs.gla.ac.uk/tops or via the main TOPS site at http://www.tops.leeds.ac.uk. Software is also available for download from these sites.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Computer Graphics*
Computer Simulation
Internet
Models, Chemical*
Models, Molecular*
Protein Conformation
Protein Folding
Proteins / analysis
Proteins / chemistry*
Sequence Alignment / methods*
Sequence Analysis, Protein / methods*
Software
User-Computer Interface*

Substances

Proteins