Characterization of a Bacillus anthracis isolate causing a rare case of fatal anthrax in a 2-year-old boy from Hong Kong

Danny T L Cheung; Kai Man Kam; Kong Lung Hau; Tak Kong Au; Chung K Marston; Jay E Gee; Tanja Popovic; Matthew N Van Ert; Leo Kenefic; Paul Keim; Alex R Hoffmaster

doi:10.1128/JCM.43.4.1992-1994.2005

Characterization of a Bacillus anthracis isolate causing a rare case of fatal anthrax in a 2-year-old boy from Hong Kong

J Clin Microbiol. 2005 Apr;43(4):1992-4. doi: 10.1128/JCM.43.4.1992-1994.2005.

Authors

Danny T L Cheung¹, Kai Man Kam, Kong Lung Hau, Tak Kong Au, Chung K Marston, Jay E Gee, Tanja Popovic, Matthew N Van Ert, Leo Kenefic, Paul Keim, Alex R Hoffmaster

Affiliation

¹ Department of Health, Hong Kong Special Administrative Region, Hong Kong, China.

Abstract

We used multiple-locus variable-number tandem repeat analysis (MLVA) and pagA sequencing to genotype a Bacillus anthracis isolate from a fatal case of human anthrax in Hong Kong. The isolate has a unique MLVA genotype, is related to the Sterne and Ames strains, and is consistent with genotypes identified in China.

Publication types

Case Reports

MeSH terms

Anthrax / microbiology*
Antigens, Bacterial / genetics*
Bacillus anthracis / classification*
Bacillus anthracis / genetics
Bacillus anthracis / isolation & purification*
Bacterial Toxins / genetics*
Bacterial Typing Techniques
Fatal Outcome
Genotype
Hong Kong
Humans
Male
Minisatellite Repeats / genetics*
Sequence Analysis, DNA

Substances

Antigens, Bacterial
Bacterial Toxins
anthrax toxin