Successful treatment of Staphylococcus epidermidis prosthetic valve endocarditis with linezolid after failure of treatment with oxacillin, gentamicin, rifampicin, vancomycin, and fusidic acid regimens

Scand J Infect Dis. 2005;37(3):173-6. doi: 10.1080/00365540410021018.

Abstract

We present a 49-y-old male, with a history of Marfan's disease and aortic and mitral valve replacement surgery, who was operated for a type III thoracoabdominal aneurysm. The postoperative course was compromised by a Staphylococcus epidermidis mitral valve endocarditis, which was successfully treated only after intravenous linezolid was included in the therapy.

Publication types

  • Case Reports

MeSH terms

  • Acetamides / administration & dosage
  • Acetamides / therapeutic use*
  • Anti-Infective Agents / administration & dosage
  • Anti-Infective Agents / therapeutic use*
  • Drug Therapy, Combination
  • Endocarditis, Bacterial / drug therapy*
  • Endocarditis, Bacterial / microbiology
  • Heart Valve Prosthesis / microbiology*
  • Humans
  • Linezolid
  • Male
  • Middle Aged
  • Mitral Valve / microbiology
  • Mitral Valve / surgery
  • Oxazolidinones / administration & dosage
  • Oxazolidinones / therapeutic use*
  • Prosthesis-Related Infections / drug therapy*
  • Prosthesis-Related Infections / microbiology
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / microbiology
  • Staphylococcus epidermidis / drug effects*
  • Treatment Failure
  • Treatment Outcome

Substances

  • Acetamides
  • Anti-Infective Agents
  • Oxazolidinones
  • Linezolid