Combined valve and coronary surgery in a patient with erythropoietic protoporphyria

J Card Surg. 2005 May-Jun;20(3):267-8. doi: 10.1111/j.1540-8191.2005.200438.x.

Abstract

Erythropoietic protoporphyria (EPP) is an autosomal dominant disorder of heme synthesis, causing excess of protoporphyrin in blood, skin, liver, and other organs. A 58-year-old male patient with EPP underwent aortic valve replacement and a concomitant aortocoronary bypass. The patient has been followed without complications due to EPP postoperatively. Cardiac surgery can safely be performed on patients with EPP by considering close attention not to stimulate porphyrin synthesis.

Publication types

  • Case Reports

MeSH terms

  • Aortic Valve Stenosis / complications
  • Aortic Valve Stenosis / diagnostic imaging
  • Aortic Valve Stenosis / surgery*
  • Combined Modality Therapy
  • Coronary Angiography
  • Coronary Artery Bypass / methods*
  • Coronary Stenosis / complications
  • Coronary Stenosis / diagnostic imaging
  • Coronary Stenosis / surgery*
  • Echocardiography, Doppler
  • Follow-Up Studies
  • Heart Valve Prosthesis Implantation / methods*
  • Humans
  • Male
  • Middle Aged
  • Protoporphyria, Erythropoietic / complications
  • Protoporphyria, Erythropoietic / diagnosis*
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome