Abstract
We describe a large outbreak involving a Klebsiella pneumoniae strain producing a plasmid-encoded ACC-1 type AmpC beta-lactamase in a hospital caring for patients with motor impairment. The epidemic strain was isolated from 57 patients in six wards between September 1999 and May 2003 and caused clinical infections in 19 patients.
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / pharmacology
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Bacterial Proteins / genetics*
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Cross Infection / epidemiology*
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Cross Infection / microbiology*
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DNA Primers
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Disabled Persons
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Drug Resistance, Bacterial
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Female
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France / epidemiology
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Hospitals, Teaching
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Humans
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Klebsiella Infections / epidemiology*
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Klebsiella Infections / microbiology*
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Klebsiella pneumoniae / enzymology*
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Klebsiella pneumoniae / genetics
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Male
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Microbial Sensitivity Tests
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Middle Aged
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Plasmids / genetics*
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Reverse Transcriptase Polymerase Chain Reaction
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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Bacterial Proteins
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DNA Primers
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AmpC beta-lactamases
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beta-Lactamases