Catalytic enantioselective arylation of aldehydes: boronic acids as a suitable source of transferable aryl groups

Chem Commun (Camb). 2005 May 21:(19):2512-4. doi: 10.1039/b501485a. Epub 2005 Apr 1.

Abstract

The catalytic enantioselective arylation of several aldehydes using boronic acids as the source of transferable aryl groups is described; the reaction is found to proceed in excellent yields and high enantioselectivities (up to 97% ee) in the presence of a chiral amino alcohol.