Quantification of cation-pi interactions in protein-ligand complexes: crystal-structure analysis of Factor Xa bound to a quaternary ammonium ion ligand

Angew Chem Int Ed Engl. 2005 Jul 11;44(28):4400-4. doi: 10.1002/anie.200500883.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites
  • Cations / chemistry
  • Computer Simulation
  • Crystallography, X-Ray
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / chemistry
  • Factor Xa / chemistry*
  • Factor Xa / metabolism
  • Ligands
  • Macromolecular Substances / chemistry
  • Models, Biological
  • Models, Chemical
  • Models, Molecular
  • Molecular Structure
  • Quaternary Ammonium Compounds / chemistry*
  • Stereoisomerism
  • Thrombin / chemistry

Substances

  • Cations
  • Enzyme Inhibitors
  • Ligands
  • Macromolecular Substances
  • Quaternary Ammonium Compounds
  • Thrombin
  • Factor Xa