Intra-Golgi transport: a way to a new paradigm?

Biochim Biophys Acta. 2005 Jul 10;1744(3):340-50. doi: 10.1016/j.bbamcr.2005.03.005. Epub 2005 Apr 1.

Abstract

The morpho-functional principles of intra-Golgi transport are, surprisingly, still not clear, which is in marked contrast to our advanced knowledge of the underlying molecular machineries. Recently, the conceptual and technological hindrances that had delayed progress in this area have been disappearing, and a cluster of powerful morphological techniques has been revealing new glimpses of the organization of traffic in intact cells. Here, we discuss the new concepts around the present models of intra-Golgi transport.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biological Transport
  • Humans
  • Models, Biological*
  • Vesicular Transport Proteins / metabolism*
  • trans-Golgi Network / metabolism*
  • trans-Golgi Network / ultrastructure

Substances

  • Vesicular Transport Proteins